دانلود مقاله انگلیسی:استفاده از عمل جراحی در درمان ER + سرطان پستان در مراحل اولیه در انگلستان: تنوع توسط زمان، سن و ویژگی های بیمار
تبریک عید فطر

20% تخفیف مقالات ترجمه شده به مناسبت عید فطر، از تیر تا 12 تیر96

ورود اعضا
توجه توجه توجه !!!!
نرم افزار winrar
پیشنهادات ویژه
پیوندهای کاربردی
پیوندهای مرتبط
مقالات انگلیسی پزشکی 1
  • The use of surgery in the treatment of ER+ early stage breast cancer in England: variation by time, age and patient characteristics

    The use of surgery in the treatment of ER+ early stage breast cancer in England: variation by time, age and patient characteristics

    سال انتشار:

    2016


    عنوان انگلیسی مقاله:

    The use of surgery in the treatment of ER+ early stage breast cancer in England: variation by time, age and patient characteristics


    ترجمه فارسی عنوان مقاله:

    استفاده از عمل جراحی در درمان ER + سرطان پستان در مراحل اولیه در انگلستان: تنوع توسط زمان، سن و ویژگی های بیمار


    منبع:

    Sciencedirect - Elsevier - European Journal of Surgical Oncology, Accepted manuscript. doi:10.1016/j.ejso.2015.12.012


    نویسنده:

    Paul Richards


    چکیده انگلیسی:

    AIM: To assess whether the proportion of patients aged 70 and over with ER+ operable breast cancer in England who are treated with surgery has changed since 2002, and to determine whether age and individual level factors including tumour characteristics and co-morbidity influence treatment choice.
    METHODS: A retrospective cohort analysis of routinely collected cancer registration data from two English regions (West Midlands, Northern & Yorkshire) was carried out (n = 17,129). Trends in surgical use over time for different age groups were assessed graphically and with linear regression. Uni- and multivariable logistic regressions were used to assess the effects of age, comorbidity, deprivation and disease characteristics on treatment choice. Missing data was handled using multiple imputation.
    RESULTS: There is no evidence of a change in the proportion of patients treated surgically over time. The multivariable model shows that age remains an important predictor of whether or not a woman with ER+ operable breast cancer receives surgery after covariate adjustment (Odds ratio of surgery vs no surgery, 0.82 (per year over 70)). Co-morbidity, deprivation, symptomatic presentation, later stage at diagnosis and low grade are also associated with increased probability of non-surgical treatment.
    CONCLUSION: Contrary to current NICE guidance in England, age appears to be an important factor in the decision to treat operable ER+ breast cancer non-surgically. Further research is needed to assess the role of other age-related factors on treatment choice, and the effect that current practice has on survival and mortality from breast cancer for older women.
    Keywords: Breast cancer | elderly | surgery | comorbidity | retrospective study


    سطح: متوسط
    تعداد صفحات فایل pdf انگلیسی: 25
    حجم فایل: 1204 کیلوبایت

    قیمت: 1000 تومان


    توضیحات اضافی:


     سفارش ترجمه مقاله


آرشیو کامل مقالات

تعداد نظرات : 0

الزامی
الزامی
الزامی
پزشکی-1
موضوعات